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KMID : 0882419930450040473
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Korean Journal of Medicine
1993 Volume.45 No. 4 p.473 ~ p.481
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The Changes of Hepatic Venous Partial Gas Pressure after Lipiodol-Transarterial Chemoembolization in Primary Hepatocellular Carcinoma
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Abstract
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ackground : This study is designed to evaluate the asfety of lipiodol-Transarteinal
chemoemboligasion (L-TAE) on the basis of oxygenation from the hepatic vein after L-TAE
whether it might be influenced to normal hepatic parenchyma of the periphery of the primary
hepatocellilan carainoma (PHC) and to find out the difference if it exists between the tumor
according to morphological features.
Method : The subjects were 14 patients with far advanced that those could be divided to
expanding & spreading type. The changes of blood gas tension obtained from the hepatic vein
were analysed before & after L-TAE.
Results :
1) The changes of hepatic PvO2 were not signigicant statistically after L-TAE in all
groups in course of times. However hepatic PvO2 increased after L-TAE in expanding type
in courses of time, but not in spreading type.
2) Hepatic PvCO2 gradusally decreased after L-TAE and significantly decreased after 20
minutes, 1 hour and 4 hours in all. The PvCO2 was significantly decreased at 4 hour after
L-TAE in expanding type, but not in spreading type.
3) Hepatic PvCO3 was significantly decreased from 5 minutes after L-TAE in all groups,
and decreased with very high significance from 20 minute after L-TAE in expanding type of
PHC, however not in spreading type.
Conclusion : This results suggest that L-TAE is safe and the response of L-TAE might
be differ from each type of PHC and post-embolization syndrome might be due to tumor
necrosis.
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KEYWORD
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